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48 Altered gut microbiota in stable patients with cystic fibrosis (CF) compared to controls and its relationship with intravenous (IV) antibiotic usage and lung function
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2015-06-05
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Burke, D., Fouhy, F., Rea, M., Harrison, M., Stanton, C., O'Sullivan, O., Murphy, D., O'Callaghan, G., Eustace, J., Shanahan, F., Fleming, C., McCarthy, M., Shortt, C., Ross, R. and Plant, B. (2015). 48 Altered gut microbiota in stable patients with cystic fibrosis (CF) compared to controls and its relationship with intravenous (IV) antibiotic usage and lung function. Journal of Cystic Fibrosis, 14, .Suppl. 1, S69. doi: https://dx.doi.org/10.1016/s1569-1993(15)30225-3
Abstract
Objective
CF is associated with altered digestive function and thus nutrient availability for gut microbes in addition to altered gut microbiota, compared with healthy controls. Equally intensive antibiotic and nutritional therapy may further compound this. We present results from the largest CF gut microbiota study to date.
