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Bacteriophage-based tools: recent advances and novel applications

O'sullivan, Lisa
Buttimer, Colin
McAuliffe, Olivia
Bolton, Declan
Coffey, Aidan
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O'Sullivan L, Buttimer C, McAuliffe O et al. Bacteriophage-based tools: recent advances and novel applications [version 1; peer review: 3 approved]. F1000Research 2016, 5(F1000 Faculty Rev):2782 (https://doi.org/10.12688/f1000research.9705.1)
Abstract
Bacteriophages (phages) are viruses that infect bacterial hosts, and since their discovery over a century ago they have been primarily exploited to control bacterial populations and to serve as tools in molecular biology. In this commentary, we highlight recent diverse advances in the field of phage research, going beyond bacterial control using whole phage, to areas including biocontrol using phage-derived enzybiotics, diagnostics, drug discovery, novel drug delivery systems and bionanotechnology.
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