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Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021
Funk, Tjede; Pharris, Anastasia; Spiteri, Gianfranco; Bundle, Nick; Melidou, Angeliki; Carr, Michael; Gonzalez, Gabriel; Garcia-Leon, Alejandro; Crispie, Fiona; O’Connor, Lois; Murphy, Niamh; Mossong, Joël; Vergison, Anne; Wienecke-Baldacchino, Anke K.; Abdelrahman, Tamir; Riccardo, Flavia; Stefanelli, Paola; Di Martino, Angela; Bella, Antonino; Lo Presti, Alessandra; Casaca, Pedro; Moreno, Joana; Borges, Vítor; Isidro, Joana; Ferreira, Rita; Gomes, João Paulo; Dotsenko, Liidia; Suija, Heleene; Epstein, Jevgenia; Sadikova, Olga; Sepp, Hanna; Ikonen, Niina; Savolainen-Kopra, Carita; Blomqvist, Soile; Möttönen, Teemu; Helve, Otto; Gomes-Dias, Joana; Adlhoch, Cornelia
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2021-04-22
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Funk Tjede, Pharris Anastasia, Spiteri Gianfranco, Bundle Nick, Melidou Angeliki, Carr Michael, Gonzalez Gabriel, Garcia-Leon Alejandro, Crispie Fiona, O’Connor Lois, Murphy Niamh, Mossong Joël, Vergison Anne, Wienecke-Baldacchino Anke K., Abdelrahman Tamir, Riccardo Flavia, Stefanelli Paola, Di Martino Angela, Bella Antonino, Lo Presti Alessandra, Casaca Pedro, Moreno Joana, Borges Vítor, Isidro Joana, Ferreira Rita, Gomes João Paulo, Dotsenko Liidia, Suija Heleene, Epstein Jevgenia, Sadikova Olga, Sepp Hanna, Ikonen Niina, Savolainen-Kopra Carita, Blomqvist Soile, Möttönen Teemu, Helve Otto, Gomes-Dias Joana, Adlhoch Cornelia, on behalf of COVID study groups. Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021. Euro Surveill. 2021;26(16):pii=2100348. https://doi.org/10.2807/1560-7917.ES.2021.26.16.2100348
Abstract
We compared 19,207 cases of SARS-CoV-2 variant B.1.1.7/S gene target failure (SGTF), 436 B.1.351 and 352 P.1 to non-variant cases reported by seven European countries. COVID-19 cases with these variants had significantly higher adjusted odds ratios for hospitalisation (B.1.1.7/SGTF: 1.7, 95% confidence interval (CI): 1.0–2.9; B.1.351: 3.6, 95% CI: 2.1–6.2; P.1: 2.6, 95% CI: 1.4–4.8) and B.1.1.7/SGTF and P.1 cases also for intensive care admission (B.1.1.7/SGTF: 2.3, 95% CI: 1.4–3.5; P.1: 2.2, 95% CI: 1.7–2.8).