Bacterial resistance to antibiotic alternatives: a wolf in sheep’s clothing?

Willing, Benjamin P; Pepin, Deanna M; Marcolla, Camila S; Forgie, Andrew J; Diether, Natalie E; Bourrie, Benjamin C T

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Bacterial resistance to antibiotic alternatives: a wolf in sheep’s clothing?

Willing, Benjamin P; Pepin, Deanna M; Marcolla, Camila S; Forgie, Andrew J; Diether, Natalie E; Bourrie, Benjamin C T

Keywords

antibiotic alternatives, resistance mechanisms, responsible use

Date

2018-04-28

Citation

B P Willing, D M Pepin, C S Marcolla, A J Forgie, N E Diether, B C T Bourrie, Bacterial resistance to antibiotic alternatives: a wolf in sheep’s clothing?, Animal Frontiers, Volume 8, Issue 2, April 2018, Pages 39–47, https://doi.org/10.1093/af/vfy003

Abstract

Implications • Substantial pressure to reduce antibiotic use has necessitated the development of antibiotic alternatives. However, relatively little consideration has been given to the development of resistance to these alternatives. • Whether we come up with antibiotic alternatives that are bacteriocidal or inhibitory, bacteria will continue to adapt and evolve. • Some antibiotic alternatives support the development of antibiotic resistance necessitating caution. • There are opportunities to optimize antibiotic alternative effectiveness as well as to minimize the development of resistance mechanisms.

Bacterial resistance to antibiotic alternatives: a wolf in sheep’s clothing?

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