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Effects of husbandry and low-dose lipopolysaccharide challenge on the acute phase response of young pigs

Llamas Moya, S.
; 
Boyle, Laura
; 
Arkins, S.
; 
Lynch, P Brendan
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Keywords
Pig welfare, herd health status, health indicators, Acute phase response mediators, intensive production systems
Date
2006-02-01
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AGRIP End of Project Reports
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http://hdl.handle.net/11019/1334
Citation
Llamas Moya, S., Boyle, L., Arkins, S., Lynch, P.B. Effects of husbandry and low-dose lipopolysaccharide challenge on the acute phase response of young pigs, End of Project Reports, Teagasc, 2006.
Abstract
The objectives of this project were to investigate: • the levels of pro-inflammatory cytokines and major porcine acute phase proteins during the first week of life of pigs; and the effect of the mentioned husbandry practices on possible age-related changes in these immunomodulators. • the effect of two methods of teeth resection and leaving the teeth intact of the skin temperature of piglets; and the impact of these teeth resection alternatives on the acute phase protein response after resection and at weaning. • the behavioural and physiological reactions of 5-day-old piglets after surgical castration. • the acute phase response elicited by low-dose LPS challenge, establishing the time-response of cytokines and acute phase proteins in both the plasma and saliva of pigs; and possible gender differences in the acute phase response in the early postweaning period. • the effect of surgical castration of 5-day-old pigs on subsequent behavioural, endocrine and immune responses elicited by low-dose LPS challenge in pigs after weaning.
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