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The Lactobacillus casei Group: History and Health Related Applications
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2018-09-10
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Hill D, Sugrue I, Tobin C, Hill C, Stanton C and Ross RP (2018) The Lactobacillus casei Group: History and Health Related Applications. Front. Microbiol. 9:2107. doi: 10.3389/fmicb.2018.02107
Abstract
The Lactobacillus casei group (LCG), composed of the closely related Lactobacillus
casei, Lactobacillus paracasei, and Lactobacillus rhamnosus are some of the most
widely researched and applied probiotic species of lactobacilli. The three species have
been extensively studied, classified and reclassified due to their health promoting
properties. Differentiation is often difficult by conventional phenotypic and genotypic
methods and therefore new methods are being continually developed to distinguish the
three closely related species. The group remain of interest as probiotics, and their use is
widespread in industry. Much research has focused in recent years on their application
for health promotion in treatment or prevention of a number of diseases and disorders.
The LCG have the potential to be used prophylactically or therapeutically in diseases
associated with a disturbance to the gut microbiota. The group have been extensively
researched with regard to stress responses, which are crucial for their survival and
therefore application as probiotics.