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dc.contributor.authorSayers, Riona
dc.contributor.authorKennedy, Aideen E.
dc.contributor.authorKrump, Lea
dc.contributor.authorSayers, Gearoid
dc.contributor.authorKennedy, Emer
dc.date.accessioned2019-10-31T12:34:43Z
dc.date.available2019-10-31T12:34:43Z
dc.date.issued2016-04-06
dc.identifier.citationSayers, R., Kennedy, A., Krump, L., Sayers, G. and Kennedy, E. An observational study using blood gas analysis to assess neonatal calf diarrhea and subsequent recovery with a European Commission-compliant oral electrolyte solution. Journal of Dairy Science, 2016, 99(6), 4647-4655. DOI: http://dx.doi.org/10.3168/jds.2015-10600en_US
dc.identifier.urihttp://hdl.handle.net/11019/1818
dc.descriptionpeer-revieweden_US
dc.description.abstractAn observational study was conducted on dairy calves (51 healthy, 31 with neonatal diarrhea) during outbreaks of diarrhea on 4 dairy farms. Clinical assessment scores (CAS) were assigned to each healthy and diarrheic calf [from 0 (healthy) to 4 (marked illness)]. Blood gas analysis [pH, base excess (BE), Na+, K+, Ca2+, Cl−, glucose, total hemoglobin, standard HCO3−, strong ion difference (SID), and anion gap (AG)] was completed for each calf. Repeated measurements were taken in healthy animals, and pre- and postintervention measurements were taken for diarrheic calves. The mean CAS of diarrheic calves was 1.7, with 51, 30, 17, and 2% of calves scoring 1, 2, 3, and 4, respectively. The mean value for blood pH, BE, AG, and SID was 7.26, −4.93 mM, 16.3 mM, and 38.59 mM, respectively. Calves were administered an oral rehydration and buffering solution (ORBS; Vitalife for Calves, Epsilion Ltd., Cork, Ireland) and reassessed. The mean CAS decreased to 0.38 (65% of calves scored 0 and 35% scored 1) at 6 to 18 h posttreatment and to 0.03 (98% of calves scored 0 and 2% scored 1) within 24 to 48 h. Significant increases in mean value for pH, BE, HCO3−, Na+, and SID, and significant decreases in AG, K+, Ca2+, and total hemoglobin were recorded posttreatment. The correlation estimates indicated that pH, HCO3−, and BE were strongly correlated with CAS, with values exceeding 0.60 in all cases. Administration of an ORBS with a high SID and bicarbonate buffer demonstrated rapid recovery from a diarrheic episode in dairy calves.en_US
dc.language.isoenen_US
dc.publisherAmerican Dairy Science Associationen_US
dc.relation.ispartofseriesJournal of Dairy Science;Vol. 99 (6)
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectacidosisen_US
dc.subjectblood gas analysisen_US
dc.subjectelectrolyteen_US
dc.subjectneonatal calf diarrheaen_US
dc.titleAn observational study using blood gas analysis to assess neonatal calf diarrhea and subsequent recovery with a European Commission-compliant oral electrolyte solutionen_US
dc.typeArticleen_US
dc.embargo.terms2017-04-06en_US
dc.identifier.doihttp://dx.doi.org/10.3168/jds.2015-10600
dc.contributor.sponsorEpsilion Ltd.en_US
dc.contributor.sponsorGrantNumberIV20151256en_US
refterms.dateFOA2017-04-06T00:00:00Z


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