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dc.contributor.authorLu, Xu
dc.contributor.authorZheng, Zhichang
dc.contributor.authorMiao, Song
dc.contributor.authorLi, Huang
dc.contributor.authorGuo, Zebin
dc.contributor.authorZhang, Yi
dc.contributor.authorZheng, Yafeng
dc.contributor.authorZheng, Baodong
dc.contributor.authorXiao, Jianbo
dc.date.accessioned2020-01-06T10:09:17Z
dc.date.available2020-01-06T10:09:17Z
dc.date.issued2017-03-09
dc.identifier.citationLu, X., Zheng, Z., Miao, S. et al. Separation of Oligosaccharides from Lotus Seeds via Medium-pressure Liquid Chromatography Coupled with ELSD and DAD. Sci Rep 7, 44174 (2017) doi:10.1038/srep44174en_US
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/11019/1851
dc.descriptionpeer-revieweden_US
dc.description.abstractLotus seeds were identified by the Ministry of Public Health of China as both food and medicine. One general function of lotus seeds is to improve intestinal health. However, to date, studies evaluating the relationship between bioactive compounds in lotus seeds and the physiological activity of the intestine are limited. In the present study, by using medium pressure liquid chromatography coupled with evaporative light-scattering detector and diode-array detector, five oligosaccharides were isolated and their structures were further characterized by electrospray ionization-mass spectrometry and gas chromatography-mass spectrometry. In vitro testing determined that LOS3-1 and LOS4 elicited relatively good proliferative effects on Lactobacillus delbrueckii subsp. bulgaricus. These results indicated a structure-function relationship between the physiological activity of oligosaccharides in lotus seeds and the number of probiotics applied, thus providing room for improvement of this particular feature. Intestinal probiotics may potentially become a new effective drug target for the regulation of immunity.en_US
dc.language.isoenen_US
dc.publisherSpringer Scienceen_US
dc.relation.ispartofseriesScientific Reports;Vol. 7(1)
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectLotus seedsen_US
dc.subjectintestinal healthen_US
dc.subjectOligosaccharidesen_US
dc.subjectevaporative light scattering detectoren_US
dc.subjectdiode-array detectoren_US
dc.subjectLactobacillus delbrueckii subsp. bulgaricusen_US
dc.subjectPhysiological activityen_US
dc.titleSeparation of Oligosaccharides from Lotus Seeds via Medium-pressure Liquid Chromatography Coupled with ELSD and DADen_US
dc.typeArticleen_US
dc.identifier.doihttps://dx.doi.org/10.1038/srep44174
dc.contributor.sponsorNational Natural Science Foundation of Chinaen_US
dc.contributor.sponsorDoctoral Program of Higher Educationen_US
dc.contributor.sponsorDepartment of Education of Fujianen_US
dc.contributor.sponsorFujian Agriculture and Forestry Universityen_US
dc.contributor.sponsorNational Nature Science Foundation of Fujianen_US
dc.contributor.sponsorFujian Province Universityen_US
dc.contributor.sponsorGrantNumber31601473en_US
dc.contributor.sponsorGrantNumber108/k41mke02aen_US
dc.contributor.sponsorGrantNumberJK2015012en_US
dc.contributor.sponsorGrantNumber612014042en_US
dc.contributor.sponsorGrantNumberKF2015099en_US
dc.contributor.sponsorGrantNumber2011J05123en_US
dc.contributor.sponsorGrantNumber2012-03en_US
dc.contributor.sponsorGrantNumbercxtd12009en_US
dc.source.volume7
dc.source.issue1
refterms.dateFOA2020-01-06T10:09:17Z


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