Show simple item record

dc.contributor.authorO'Donovan, Ciara M.
dc.contributor.authorConnor, Brendan
dc.contributor.authorMadigan, Sharon
dc.contributor.authorCotter, Paul D.
dc.contributor.authorO'Sullivan, Orla
dc.creatorCiara M., O’ Donovan
dc.date.accessioned2020-06-04T15:38:22Z
dc.date.available2020-06-04T15:38:22Z
dc.date.issued2020-01-11
dc.identifier.citationO’ Donovan CM, Connor B, Madigan SM, Cotter PD, O’ Sullivan O. Instances of altered gut microbiomes among Irish cricketers over periods of travel in the lead up to the 2016 World Cup: A sequencing analysis. Travel Medicine and Infectious Disease 2020:101553; doi https://doi.org/10.1016/j.tmaid.2020.101553en_US
dc.identifier.issn14778939
dc.identifier.urihttp://hdl.handle.net/11019/1926
dc.descriptionpeer-revieweden_US
dc.description.abstractBackgroundChanges and stresses experienced during travel have the potential to impact the gut microbiome, with travel implicated in the spread of antibiotic resistance genes across continents. The possibility of gut microbiome-mediated negative impacts arising from travel, and consequences for peak performance, would be of particular concern for elite athletes. MethodsFaecal samples were collected from male (N = 14) and female (N = 7) cricket players during the build-up to the 2016 Cricket World Cup. Baseline and post-travel samples were collected from all participants and subjected to 16S rRNA amplicon sequencing. Samples from a subset of participants (N = 4) were also analysed by shotgun metagenomic sequencing. ResultsAnalysis revealed a single travel time point as having the potential to have an impact on the gut microbiome. Reductions in alpha diversity following travel were observed, accompanied by shifts in the taxonomic profile of the gut microbiome. Antibiotic resistance and virulence genes were also identified as undergoing changes following travel. ConclusionsThis study reveals that periods of travel, in particular following gastrointestinal distress, may result in gut microbiome disruption. While this analysis was completed in athletes, the findings are applicable to all travelling individuals and considerations should be made surrounding travel in an attempt to reduce these changes.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofTravel Medicine and Infectious Disease
dc.relation.ispartofseriesTravel Medicine and Infectious Disease;
dc.rights© 2020 The Authors. Published by Elsevier Ltd.
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectTravelen_US
dc.subjectGut microbiomeen_US
dc.subjectGut distressen_US
dc.subjectExerciseen_US
dc.subjectAntibiotic resistanceen_US
dc.subjectVirulenceen_US
dc.titleInstances of altered gut microbiomes among Irish cricketers over periods of travel in the lead up to the 2016 World Cup: A sequencing analysisen_US
dc.typeArticleen_US
dc.embargo.terms2021-01-11en_US
dc.identifier.doihttps://doi.org/10.1016/j.tmaid.2020.101553
dc.identifier.eid1-s2.0-S147789392030003X
dc.identifier.piiS1477-8939(20)30003-X
dc.contributor.sponsorScience Foundation Irelanden_US
dc.contributor.sponsorGrantNumberSFI/12/RC/2273en_US
dc.contributor.sponsorGrantNumber13/SIRG/2160en_US
dc.contributor.sponsorGrantNumber11/PI/1137en_US
dc.source.beginpage101553


Files in this item

Thumbnail
Name:
Instances-of-altered-gut-micro ...
Size:
1.701Mb
Format:
PDF
Description:
main article

This item appears in the following Collection(s)

Show simple item record

© 2020 The Authors. Published by Elsevier Ltd.
Except where otherwise noted, this item's license is described as © 2020 The Authors. Published by Elsevier Ltd.