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dc.contributor.authorOriach, Clara Seira
dc.contributor.authorRobertson, Ruairi C
dc.contributor.authorSTANTON, CATHERINE
dc.contributor.authorCryan, John F.
dc.contributor.authorDinan, Timothy G.
dc.date.accessioned2020-06-18T11:57:04Z
dc.date.available2020-06-18T11:57:04Z
dc.date.issued2016-01-21
dc.identifier.citationOriach, C., Robertson, R., Stanton, C., Cryan, J. and Dinan, T. (2016). Food for thought: The role of nutrition in the microbiota-gut–brain axis. Clinical Nutrition Experimental, [online] 6, pp.25-38. Available at: https://dx.doi.org/10.1016/j.yclnex.2016.01.003en_US
dc.identifier.urihttp://hdl.handle.net/11019/2020
dc.descriptionpeer-revieweden_US
dc.description.abstractRecent research has provided strong evidence for the role of the commensal gut microbiota in brain function and behaviour. Many potential pathways are involved in this bidirectional communication between the gut microbiota and the brain such as immune mechanisms, the vagus nerve and microbial neurometabolite production. Dysbiosis of gut microbial function has been associated with behavioural and neurophysical deficits, therefore research focused on developing novel therapeutic strategies to treat psychiatric disorders by targeting the gut microbiota is rapidly growing. Numerous factors can influence the gut microbiota composition such as health status, mode of birth delivery and genetics, but diet is considered among the most crucial factors impacting on the human gut microbiota from infancy to old age. Thus, dietary interventions may have the potential to modulate psychiatric symptoms associated with gut–brain axis dysfunction. Further clinical and in vivo studies are needed to better understand the mechanisms underlying the link between nutrition, gut microbiota and control of behaviour and mental health.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofseriesClinical Nutrition Experimental;Vol. 6
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectdieten_US
dc.subjectPsychobioticsen_US
dc.subjectGut microbiotaen_US
dc.subjectGut–brain axisen_US
dc.subjectPsychiatric disordersen_US
dc.titleFood for thought: The role of nutrition in the microbiota-gut–brain axisen_US
dc.typeArticleen_US
dc.embargo.terms2017-01-21en_US
dc.identifier.doihttps://dx.doi.org/10.1016/j.yclnex.2016.01.003
dc.contributor.sponsorScience Foundation Irelanden_US
dc.contributor.sponsorHealth Research Board of Irelanden_US
dc.contributor.sponsorSea Change Strategy NutraMara programmeen_US
dc.contributor.sponsorSMART FOOD projecten_US
dc.contributor.sponsorDepartment of Agriculture, Food and the Marineen_US
dc.contributor.sponsorMarine Instituteen_US
dc.contributor.sponsorGrantNumberSFI/12/RC/2273en_US
dc.contributor.sponsorGrantNumberHRA_POR/2011/23en_US
dc.contributor.sponsorGrantNumberHRA_POR/2012/32en_US
dc.contributor.sponsorGrantNumberMFFRI/07/01en_US
dc.contributor.sponsorGrantNumber13/F/411en_US
refterms.dateFOA2017-01-21T00:00:00Z


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