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dc.contributor.authorDinan, Timothy G.
dc.contributor.authorStilling, Roman M.
dc.contributor.authorSTANTON, CATHERINE
dc.contributor.authorCryan, John F.
dc.date.accessioned2020-06-30T11:37:36Z
dc.date.available2020-06-30T11:37:36Z
dc.date.issued2015-03-03
dc.identifier.citationDinan, T., Stilling, R., Stanton, C. and Cryan, J. Collective unconscious: How gut microbes shape human behavior. Journal of Psychiatric Research, 2015, 63, 1-9. doi: https://dx.doi.org/10.1016/j.jpsychires.2015.02.021en_US
dc.identifier.urihttp://hdl.handle.net/11019/2099
dc.descriptionpeer-revieweden_US
dc.description.abstractThe human gut harbors a dynamic and complex microbial ecosystem, consisting of approximately 1 kg of bacteria in the average adult, approximately the weight of the human brain. The evolutionary formation of a complex gut microbiota in mammals has played an important role in enabling brain development and perhaps sophisticated social interaction. Genes within the human gut microbiota, termed the microbiome, significantly outnumber human genes in the body, and are capable of producing a myriad of neuroactive compounds. Gut microbes are part of the unconscious system regulating behavior. Recent investigations indicate that these microbes majorly impact on cognitive function and fundamental behavior patterns, such as social interaction and stress management. In the absence of microbes, underlying neurochemistry is profoundly altered. Studies of gut microbes may play an important role in advancing understanding of disorders of cognitive functioning and social interaction, such as autism.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofseriesJournal of Psychiatric Research;Vol. 63
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectMicrobiotaen_US
dc.subjectMicrobiomeen_US
dc.subjectGut–brain axisen_US
dc.subjectSocial behavioren_US
dc.subjectAutismen_US
dc.subjectPsychobioticsen_US
dc.titleCollective unconscious: How gut microbes shape human behavioren_US
dc.typeArticleen_US
dc.embargo.terms2016-03-03en_US
dc.identifier.doihttps://dx.doi.org/10.1016/j.jpsychires.2015.02.021
dc.contributor.sponsorScience Foundation Irelanden_US
dc.contributor.sponsorHealth Research Boarden_US
dc.contributor.sponsorEuropean Unionen_US
dc.contributor.sponsorGrantNumberSFI/12/RC/2273en_US
dc.contributor.sponsorGrantNumberHRA_POR/2011/23en_US
dc.contributor.sponsorGrantNumberHRA_POR/2012/32en_US
dc.contributor.sponsorGrantNumberFP7/2007-2013en_US
refterms.dateFOA2016-03-03T00:00:00Z


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