Show simple item record

dc.contributor.authorYang, Bo
dc.contributor.authorYan, Shuang
dc.contributor.authorChen, Yang
dc.contributor.authorRoss, R. Paul
dc.contributor.authorSTANTON, CATHERINE
dc.contributor.authorZhao, Jianxin
dc.contributor.authorZhang, Hao
dc.contributor.authorChen, Wei
dc.date.accessioned2020-11-18T15:52:11Z
dc.date.available2020-11-18T15:52:11Z
dc.date.issued2020-07-24
dc.identifier.citationYang, B.; Yan, S.; Chen, Y.; Ross, R.P.; Stanton, C.; Zhao, J.; Zhang, H.; Chen, W. Diversity of Gut Microbiota and Bifidobacterial Community of Chinese Subjects of Different Ages and from Different Regions. Microorganisms 2020, 8, 1108. https://doi.org/10.3390/microorganisms8081108en_US
dc.identifier.urihttp://hdl.handle.net/11019/2355
dc.descriptionpeer-revieweden_US
dc.description.abstractGut microbiota composition and functionality are closely linked to host health. In this study, the fecal microbiota and bifidobacterial communities of 111 healthy volunteers from four regions of China of varying age profiles (Child, 1–5 years; Young, 18–50 years; Elder, 60–80 years; Longevity, ≥90 years) were investigated via high-throughput sequencing. Canonical analysis revealed that the gut microbiota, as well as bifidobacteria profiles of the subjects, clustered according to their regions and age. Eight genera were shared among all subjects, however, certain genera distributed differently in subjects grouped by region and age. Faecalibacterium was enriched in samples from Zhongxiang, unclassified Ruminococcaceae and Christensenellaceae were enriched in the Longevity group, and Bifidobacterium was enriched in Child. Within Bifidobacterium, B. longum was the most abundant species in almost all samples except for Child, in which B. pseudocatenulatum was the most abundant. Additionally, the abundances of B. adolescentis and B. dentium were lower in Child. In conclusion, our results suggest that geography and age affect the structure of the gut microbiota, as well as Bifidobacterium composition, and this variation may greatly associate with the metabolic and immune changes that occur during the process of aging.en_US
dc.description.sponsorshipNational Natural Science Foundation of China-Guangdong Joint Fund
dc.language.isoenen_US
dc.publisherMDPI AGen_US
dc.relation.ispartofseriesMicroorganisms;1108
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectChinese subjectsen_US
dc.subjectgut microbiotaen_US
dc.subjectbifidobacterial communityen_US
dc.subjectdiversityen_US
dc.subjectregionen_US
dc.subjectageen_US
dc.titleDiversity of Gut Microbiota and Bifidobacterial Community of Chinese Subjects of Different Ages and from Different Regionsen_US
dc.typeArticleen_US
dc.identifier.doihttps://doi.org/10.3390/microorganisms8081108
dc.contributor.sponsorNational Natural Science Foundation of Chinaen_US
dc.contributor.sponsorNational First-Class Discipline Program of Food Science and Technologyen_US
dc.contributor.sponsorFundamental Research Funds for the Central Universitiesen_US
dc.contributor.sponsorCollaborative Innovation Center of Food Safety and Quality Control in Jiangsu Provinceen_US
dc.contributor.sponsorGrantNumber31820103010en_US
dc.contributor.sponsorGrantNumber31530056en_US
dc.contributor.sponsorGrantNumberJUFSTR20180102en_US
dc.contributor.sponsorGrantNumberJUSRP52003Ben_US
dc.source.volume8
dc.source.issue8
dc.source.beginpage1108
refterms.dateFOA2020-11-18T15:52:12Z
dc.source.journaltitleMicroorganisms


Files in this item

Thumbnail
Name:
microorganisms-08-01108.pdf
Size:
4.763Mb
Format:
PDF
Description:
main article

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-ShareAlike 4.0 International
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 4.0 International