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dc.contributor.authorCodagnone, Martin G.
dc.contributor.authorSTANTON, CATHERINE
dc.contributor.authorO'Mahony, Siobhain M.
dc.contributor.authorDinan, Timothy G.
dc.contributor.authorCryan, John F.
dc.date.accessioned2021-04-11T16:29:20Z
dc.date.available2021-04-11T16:29:20Z
dc.date.issued2019-06-24
dc.identifier.citationCodagnone M, G, Stanton C, O’Mahony S, M, Dinan T, G, Cryan J, F: Microbiota and Neurodevelopmental Trajectories: Role of Maternal and Early-Life Nutrition. Ann Nutr Metab 2019;74(suppl 2):16-27. https://doi.org/10.1159/000499144en_US
dc.identifier.urihttp://hdl.handle.net/11019/2394
dc.descriptionpeer-revieweden_US
dc.description.abstractPregnancy and early life are characterized by marked changes in body microbial composition. Intriguingly, these changes take place simultaneously with neurodevelopmental plasticity, suggesting a complex dialogue between the microbes that inhabit the gastrointestinal tract and the brain. The purpose of this chapter is to describe the natural trajectory of microbiota during pregnancy and early life, as well as review the literature available on its interaction with neurodevelopment. Several lines of evidence show that the gut microbiota interacts with diet, drugs and stress both prenatally and postnatally. Clinical and preclinical studies are illuminating how these disruptions result in different developmental outcomes. Understanding the role of the microbiota in neurodevelopment may lead to novel approaches to the study of the pathophysiology and treatment of neuropsychiatric disorders.en_US
dc.language.isoenen_US
dc.publisherS. Karger AGen_US
dc.relation.ispartofseriesAnnals of Nutrition and Metabolism;
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttps://www.karger.com/Services/SiteLicenses
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectMicrobiotaen_US
dc.subjectNeuropsychiatryen_US
dc.subjectGut-brain axisen_US
dc.subjectBrain developmenten_US
dc.subjectEarly lifeen_US
dc.subjectStressen_US
dc.subjectDieten_US
dc.subjectNutritionen_US
dc.titleMicrobiota and Neurodevelopmental Trajectories: Role of Maternal and Early-Life Nutritionen_US
dc.typeArticleen_US
dc.identifier.doihttps://doi.org/10.1159/000499144
dc.contributor.sponsorScience Foundation Irelanden_US
dc.contributor.sponsorEuropean Unionen_US
dc.contributor.sponsorNestlé Nutrition Instituteen_US
dc.contributor.sponsorGrantNumber754535en_US
dc.contributor.sponsorGrantNumber12/RC/2273en_US
dc.source.volume74
dc.source.issueSuppl. 2
dc.source.beginpage16
dc.source.endpage27
refterms.dateFOA2021-04-11T16:29:21Z
dc.source.journaltitleAnnals of Nutrition and Metabolism


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