Bacterial resistance to antibiotic alternatives: a wolf in sheep’s clothing?
AuthorWilling, Benjamin P
Pepin, Deanna M
Marcolla, Camila S
Forgie, Andrew J
Diether, Natalie E
Bourrie, Benjamin C T
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CitationB P Willing, D M Pepin, C S Marcolla, A J Forgie, N E Diether, B C T Bourrie, Bacterial resistance to antibiotic alternatives: a wolf in sheep’s clothing?, Animal Frontiers, Volume 8, Issue 2, April 2018, Pages 39–47, https://doi.org/10.1093/af/vfy003
AbstractImplications • Substantial pressure to reduce antibiotic use has necessitated the development of antibiotic alternatives. However, relatively little consideration has been given to the development of resistance to these alternatives. • Whether we come up with antibiotic alternatives that are bacteriocidal or inhibitory, bacteria will continue to adapt and evolve. • Some antibiotic alternatives support the development of antibiotic resistance necessitating caution. • There are opportunities to optimize antibiotic alternative effectiveness as well as to minimize the development of resistance mechanisms.
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