Show simple item record

dc.contributor.authorMatthews, Chloe
dc.contributor.authorCotter, Paul D
dc.contributor.authorO’ Mahony, Jim
dc.date.accessioned2021-12-22T16:07:11Z
dc.date.available2021-12-22T16:07:11Z
dc.date.issued2021-05-07
dc.identifier.citationMatthews, C., Cotter, P.D. & O’ Mahony, J. MAP, Johne’s disease and the microbiome; current knowledge and future considerations. anim microbiome 3, 34 (2021). https://doi.org/10.1186/s42523-021-00089-1en_US
dc.identifier.urihttp://hdl.handle.net/11019/2747
dc.descriptionpeer-revieweden_US
dc.description.abstractMycobacterium avium subsp. paratuberculosis is the causative agent of Johne’s disease in ruminants. As an infectious disease that causes reduced milk yields, effects fertility and, eventually, the loss of the animal, it is a huge financial burden for associated industries. Efforts to control MAP infection and Johne’s disease are complicated due to difficulties of diagnosis in the early stages of infection and challenges relating to the specificity and sensitivity of current testing methods. The methods that are available contribute to widely used test and cull strategies, vaccination programmes also in place in some countries. Next generation sequencing technologies have opened up new avenues for the discovery of novel biomarkers for disease prediction within MAP genomes and within ruminant microbiomes. Controlling Johne’s disease in herds can lead to improved animal health and welfare, in turn leading to increased productivity. With current climate change bills, such as the European Green Deal, targeting livestock production systems for more sustainable practices, managing animal health is now more important than ever before. This review provides an overview of the current knowledge on genomics and detection of MAP as it pertains to Johne’s disease.en_US
dc.language.isoenen_US
dc.publisherBiomed Centralen_US
dc.relation.ispartofseriesAnimal microbiome;
dc.subjectMycobacterium avium subsp. paratuberculosisen_US
dc.subjectJohne’s disease (JD)en_US
dc.subjectmicrobiomeen_US
dc.titleMAP, Johne’s disease and the microbiome; current knowledge and future considerationsen_US
dc.typeArticleen_US
dc.date.updated2021-05-09T03:11:55Z
dc.language.rfc3066en
dc.rights.holderThe Author(s)
dc.identifier.doihttps://doi.org/10.1186/s42523-021-00089-1
dc.contributor.sponsorDepartment of Agriculture, Food and the Marineen_US
dc.contributor.sponsorGrantNumber15/S/651en_US
refterms.dateFOA2021-12-22T16:07:12Z


Files in this item

Thumbnail
Name:
42523_2021_Article_89.pdf
Size:
1.035Mb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record