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dc.contributor.authorSheehan, Maresa
dc.contributor.authorPesavento, Patricia A.
dc.contributor.authorCampion, Francis
dc.contributor.authorLynch, John
dc.contributor.authorMcGettrick, Shane
dc.contributor.authorToland, Brian
dc.contributor.authorKennedy, Aideen
dc.date.accessioned2024-06-07T15:24:22Z
dc.date.available2024-06-07T15:24:22Z
dc.date.issued2024-05-04
dc.identifier.citationIrish Veterinary Journal. 2024 May 04;77(1):7
dc.identifier.urihttps://doi.org/10.1186/s13620-024-00269-w
dc.identifier.urihttp://hdl.handle.net/11019/3700
dc.description.abstractAbstract Background Ovine gammaherpesvirus 2 (OvHV-2) is the causative agent of sheep associated malignant catarrhal fever (MCF). As sheep are the adapted host for OvHV-2, it is generally presumed that infection is not associated with disease in this species. However, a recent case review combined in-situ hybridisation, PCR and histopathology and correlated the viral distribution with systemic necrotizing vasculitis and concluded OvHV-2 was the likely agent responsible for sporadic, MCF-like vascular disease in sheep. Case presentation Using similar methods this case study reports on the findings of the first reported cases in an Irish Flock of MCF- like systemic necrotizing vasculitis in sheep associated with OvHV-2. Sheep A, a 16-month-old Texel-cross hogget displayed signs of ill- thrift, Sheep B, a nine-month-old Belclare-cross lamb, was found dead having displayed no obvious symptoms. Both cases occurred on the same farm, however the animals were not related. Lymphohistiocytic vasculitis of various tissues was the predominant histopathological finding in both animals. Conclusion By combining histopathology, PCR and in-situ hybridisation results, MCF- like systemic necrotizing vasculitis associated with OvHV-2 has been diagnosed for the first time in an Irish flock.
dc.titleFirst reported case in an Irish flock of MCF- like systemic necrotizing vasculitis in sheep associated with ovine herpesvirus 2
dc.typeJournal Article
dc.date.updated2024-05-05T03:14:48Z
dc.language.rfc3066en
dc.rights.holderThe Author(s)
refterms.dateFOA2024-06-07T15:24:26Z


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