Gut microbes from the phylogenetically diverse genus Eubacterium and their various contributions to gut health

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dc.contributor.authorMukherjee, Arghya
dc.contributor.authorLordan, Cathy
dc.contributor.authorRoss, R. Paul
dc.contributor.authorCotter, Paul D.
dc.contributor.sponsorDepartment of Agriculture, Food and the Marineen_US
dc.contributor.sponsorTeagasc Walsh Fellowshipen_US
dc.contributor.sponsorScience Foundation Irelanden_US
dc.contributor.sponsorEUen_US
dc.contributor.sponsorGrantNumber15/F/635en_US
dc.contributor.sponsorGrantNumber2017047en_US
dc.contributor.sponsorGrantNumberSFI/12/RC/2273en_US
dc.contributor.sponsorGrantNumberSFI/16/RC/3835en_US
dc.contributor.sponsorGrantNumber818368en_US
dc.date.accessioned2021-07-21T11:26:26Z
dc.date.available2021-07-21T11:26:26Z
dc.date.issued2020-08-23
dc.descriptionpeer-revieweden_US
dc.description.abstractOver the last two decades our understanding of the gut microbiota and its contribution to health and disease has been transformed. Among a new ‘generation’ of potentially beneficial microbes to have been recognized are members of the genus Eubacterium, who form a part of the core human gut microbiome. The genus consists of phylogenetically, and quite frequently phenotypically, diverse species, making Eubacterium a taxonomically unique and challenging genus. Several members of the genus produce butyrate, which plays a critical role in energy homeostasis, colonic motility, immunomodulation and suppression of inflammation in the gut. Eubacterium spp. also carry out bile acid and cholesterol transformations in the gut, thereby contributing to their homeostasis. Gut dysbiosis and a consequently modified representation of Eubacterium spp. in the gut, have been linked with various human disease states. This review provides an overview of Eubacterium species from a phylogenetic perspective, describes how they alter with diet and age and summarizes its association with the human gut and various health conditions.en_US
dc.embargo.terms2021/08/23en_US
dc.identifier.citationA. Mukherjee, C. Lordan, R. P. Ross & P. D. Cotter (2020) Gut microbes from the phylogenetically diverse genus Eubacterium and their various contributions to gut health, Gut Microbes, 12:1, https://doi.org/10.1080/19490976.2020.1802866en_US
dc.identifier.doihttps://doi.org/10.1080/19490976.2020.1802866
dc.identifier.urihttp://hdl.handle.net/11019/2485
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.relation.ispartofseriesGut Microbes;12
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectEubacteriumen_US
dc.subjectgut microbiotaen_US
dc.subjectshort-chain fatty acidsen_US
dc.subjectEubacterium halliien_US
dc.subjectEubacterium rectaleen_US
dc.subjectbutyrateen_US
dc.subjectirritable bowel syndromeen_US
dc.subjectphylogenyen_US
dc.subjectbile acidsen_US
dc.subjectcholesterolen_US
dc.titleGut microbes from the phylogenetically diverse genus Eubacterium and their various contributions to gut healthen_US
dc.typeArticleen_US
dspace.entity.typePublication
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